Woman Writing Candace Hoffmann

medical journalist, author, advocate

Provillus - Just another name for Rogaine?

Posted By candace on July 2, 2009

Since engaging TweetDeck and using the search feature for #hair loss, I’ve been amazed at the amount of “information” out there. One product Tweeted constantly from many sources is Provillus. At first I dismissed it, but then when I went the product’s Web site  , I decided to see what it’s about.

First the Provillus homepage says “contains FDA approved ingredient for hair regrowth.” Yup, it contains topical minoxidil(Rogaine). But it is the ingredient that is FDA approved NOT Provillus. Provillus has two formulations — one for men and one for women.  For this report I am going to concentrate on the formulation for women.

Provillus uses a two-pronged approach to hair loss:

  • A 2 percent topical minoxidil solution
  • An oral supplement.

I give Provillus credit for being so upfront about the active ingredients for both of these products. All the information is there for everyone to read. And I suggest reading them and then looking them up.

Is the supplement safe?

My concern, and those of you who have read my book know this is a sticking point of mine, is the supplement. The supplement contains Vitamin B6 (4 mg); Biotin (10 mg), Magnesium (150 mg) and its 1,200 mg proprietary blend of Horsetail Silica (Equesetum arvense) and pare-Amino-Benzoic Acid (PABA).

While I have concern about the vitamins, it’s the proprietary blend I have the most issues with.

Horsetail silica (E. arvense)

This herb has been around for thousands of years. According to the University of Maryland’smedical reference library it has been used to stop bleeding, heal ulcers, ounds, treat tuberculosis and kidney problems MedLine Plus, a service of the U.S. National Library of Medicine and the National Institutes of Medicine, note that E. arvense is approved in Germany for use as a diuretic and there are claims it may help increase bone density. So far so good.

However, both sources list a host of side effects and possible interactions. I won’t list them all here, but do hope you will link to the sites, especially if you are taking any medications. Here’s a partial list:

  • May deplete vitamin B1 (thiamin) when used regularly.
  • May enhance toxic effects of certain medications such as digoxin, phenytoin, nicotine
  • Should not be taken if pregnant or breast feeding
  • Could cause adverse reaction for people taking diuretics, steroids laxitives, antigout agents, ephedra and licorice.

PABA
You have probably heard of this as it’s an active ingredient in some sun screens and some people have an allergic reaction to it when used topically. Taken orally, PDRHealthnotes people should not take more than 400 mg of it without consulting a physician. Possible side effects inclue breathing problems, chest pain, rash.

Looking at these two ingredients alone gives me pause. And to be fair, Provillus does include precautions about both its topical solution and its supplement. However, since Horsetail is known to deplete B1, why not include B1 in the formulation?

Another question is how many milligrams of PABA are in the proprietary blend. Is it below the recommended tolerable upper limit of 400 mg? We don’t know.

As for the B6, biotin and magnesium, they too come with their side effects, but I’m less concerned with them but wonder why this blend? Biotin and folic acid are typically seen as the hair loss dynamic duo (although they mostly just help hair stay healthy and strong, not regrow hair). A good B vitamin formulation or a good multivitamin is just as well and you will avoid overdosing.

As for horsetail and PABA — in my opinion, it would be wise to avoid them.

However, if you decide to try Provillus or are currently taking Provillus, please tell you physician that you are taking this supplement. Especially if you are taking any other medication — over-the-counter or prescription — or if you are taking other herbs and supplements. A quick example of a biotin interaction – it can enhance the effects of cholesterol-lowering drugs such as Lipitor, and should probably be avoided if you are taking statins. Enhancement of statins is not good as it means there is too much of the drug in your system, which could cause liver damage. Your physician monitors your liver function when you are on these drugs. So be sure to come clean with all the supplements you take.

Cost
Since Provillus’ active and proven hair regrowth ingredient is topical minoxidil, you should weigh the cost agains the cost of Rogaine and other generic brands of minoxidil. 

Another consideration, if you’ve been using topical minoxidil whether as Rogaine or a generic and it’s working for you, why buy the same thing under another label, unless it’s less expensive. And, if it has not been working for you, why bother to buy the same thing under another name? A rose is a rose.

Warning:If you are a woman and think you might get more bang for your buck by buying the men’s formulation of Provillus, think again.  While the 5 percent minoxidil in the topical solution may not hurt you, the men’s supplement contains saw palmetto, which for women could cause some unwanted side effects, particularly if you are still menstruating, pregnant or breast feeding. Again, if you decide to take such supplements, please speak with a health care professional. In future posts I’ll discuss saw palmetto as well.

Here’s another good article on Provillus from the American Hair Loss Association.

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Hair loss help or hair loss scams — let’s check the facts

Posted By candace on July 2, 2009

One of the reasons I wrote Breaking the Silence on Women’s Hair Loss was to help women navigate the glut of good and mostly bad information on the Internet and in literature about hair loss.

I have thought long and hard about how to use this Web site as I saw no reason to try to compete with good existing Web site such as those listed on my blog roll. However, with the advent of instant information via social media vehicles such as Twitter as well as a new glut of blogs, articles written by amateurs who do not know how to properly source an article, and an increase of forums where people exchange both good and bad information, I feel it’s time to more actively enter the fray; to complement the good Web sites out there, and counter the bad.

I’m particulary concerned about product claims and so in my next post will tackle the claims by Provillus. Click on nearly any #hair loss Tweet and it will take you to a page to buy Provillus. So we’ll take a look at the claims.

I’d love to hear what products you are using and how you like them and how they are working for you. Anything from shampoos to topical solutions to hair prostheses to supplements. I’ll share products I use and like as well. For instance, I love Aveda products and Aveda salons. I feel their products are gentle on my hair, albeit pricey. I also recently discovered Nisim shampoo, which I believe can only be bought over the Internet. I’m going to take a closer look at it. A bottle was given to me during my book tour and it really seemed to make a difference on my hair. I was also given a Leimo, low-light laser comb (Like HairMax) — and boy are my arms tired. Does it work? Stay tuned.

In future posts I’ll discuss, Rogaine, HairChi, Volluma and others. Tell me what you want to hear about.

Let’s break the silence. Consider me your guide to information and misinformation about hair loss. Did you recently click on a link for Provillus? Considering buying it? Read about this product here.

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Facebook Fan page for women’s hair loss book

Posted By candace on May 31, 2009

Please join the fan page for Breaking the Silence on Women’s Hair Loss. Enter the discussions and help me break the silence. I want to hear from you here or there! Or write to me at choff@herloss.org. I look forward to hearing from you.

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Sox21 gene making headlines in hair loss

Posted By candace on May 28, 2009

Research reported in the Proceedings of the National Academy of Sciences journal appear to be closing in on a gene - SOX21 that may hold the key to hair loss. Blocking this gene caused mice to become bald.

The gene could hold a clue for how hair loss happens in humans. Read more about the study here.

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Join me in San Diego for Free Seminar on Hair Loss

Posted By candace on April 30, 2009

I will be speaking about women’s hair loss 4:30 p.m. Sunday, May 3 at the Country Inn & Suites by Carlson, 5975 Lusk Blvd, San Diego. Call 858-404-0044 or 858-688-1627 to reserve your spot. Receive a free copy of my book and consultation for those attending.

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